Urobilin and Allied Pigments

Urobilin Physiology and Pathology

Further evidence is presented, in addition to that of our previous papers, that the intestinal tract is, under ordinary circumstances, the sole place of origin of urobilin. So long as the biliary tract remains sterile the presence of the pigment in bile and urine is entirely dependent upon the passage of bile to the intestine. Animals rendered urobilin-free by the collection of all the bile fro...

Cxlvii. Studies on Bile Pigments. Iii. the Quantitative Determination of Urobilin and Urobilinogen in Urine and Faeces

IN a previous paper [Naumann, 1936] the qualitative tests for urobilinogen and urobilin have been studied. In the following the quantitative aspect of the problem is treated. A basis for the estimation of urobilin and related compounds was first introduced by Terwen [1924; 1925]. The main features of this method consist in determining the sum of urobilinogen and urobilin as urobilinogen after r...

Studies on Urobilin Physiology and Pathology

Experimental infection of the intubated and previously sterile biliary tract of the dog with particles of the stools leads to a formation of urobilin from the bilirubin of the bile as it flows through the ducts. No urobilinuria occurs, however, unless temporary biliary obstruction is produced, or the liver parenchyma injured. Then urobilinuria develops, despite the fact that no bile is reaching...

A further study of crystalline d-urobilin.

The isolation of a crystalline dextrorotatory d-urobilin hydrochloride from infected fistula bile was reported from this laboratory a number of years ago (1). Recently this substance has also been obtained from the feces of patients whose fecal flora has been altered by Aureomycin or Terramycin (2). This has been confirmed by James et al. (3). In these earlier studies the substance was isolated...

Arthritis and Allied Conditions